More than a decade of basic research and clinical evidence now implicates inflammatory processes in the pathogenesis of Alzheimer’s disease (AD). TNF-alpha is a pro-inflammatory
The latest issue of Life Extension Magazine (August 2008) contains an encouraging report about off-label use of etanercept (commercial name: Enbrel) to reverse the cognitive
Induction of hypothermia can reduce injury to the brain when it is deprived of oxygen. How fast do we need to cool a patient during
As discussed in a previous post, perfusion of the brain following long-term (>5 min) ischemia has been shown to be significantly compromised, particularly in subcortical
Cryopreservation of the brain depends on the removal of blood from the brain’s vasculature and its replacement with cryoprotective solutions in order to prevent ice
A shorter version of this article appeared in Cryonics, Spring 2006 The goal of human cryopreservation standby and stabilization procedures is to preserve the structure
Introduction In everyday or emergency medical practice, intranasal (IN) administration of therapeutic agents (i.e., drug delivery via the nose) offers several advantages over oral, intravenous,
Neuroprotective agents for stroke continue to fail in clinical trials. One important reason is that the therapeutic window for many of those agents is too
“People like you and I, though mortal of course like everyone else, do not grow old no matter how long we live…[We] never cease to
Because the current generation of vitrification agents permit cryopreservation of the brain without ice formation, the current objective of cryonics research is maintenance of viability